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Currently, most diagnostic genetic services utilize dna extracted from somatic tissues, for example blood or saliva, where the genetic information is not transmitted to the next generation. Analysis.
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Together, our data lead to a molecular model, in which a hierarchical series of binding events achieve meiotic telomere attachment through TRF1-mediated loading of telomeric DNA to the meiotic.
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The pathogenicity of the mutation was studied by transport assays, computer modeling, followed by targeted metabolic testing and in vitro studies. Age-matched control and patient fibroblasts from.
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