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Using a similar approach as detailed in supplementary figure 1 we detected mitochondria located specifically within selected dopaminergic synapses based on two parameters, those which contained.
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Severe telomere dysfunction is induced by telomere shortening in late-generation telomerase (terc /) knockout mice, where it compromises the function of tissue-specific stem and progenitor cells,
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Exogenous pathway optimization and chassis engineering are two crucial methods for heterologous pathway expression. The two methods are normally carried out step-wise and in a trial-and-error manner.
Senescent cells accumulate in human tissues during ageing and contribute to age-related pathologies. The mechanisms responsible for their accumulation are unclear. Here we show that senescent dermal.
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The project was approved by the Faculty of Medical Sciences Ethical Review Committee, Newcastle University. After cooling down to room temperature, the slides were washed twice with distilled water.
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